Tuesday, August 28, 2012

Isolated mononeuropathy multiplex-a rare manifestation of intravascular large B-cell lymphoma.


Isolated mononeuropathy multiplex-a rare manifestation of intravascular large B-cell lymphoma.


Sept 2012

Source

*Department of Neurology, St Elizabeth's Medical Center, Boston, MA †Department of Neuropathology, Brigham and Women's Hospital, Boston, MA.

Abstract


ABSTRACT: Intravascular large B-cell lymphoma, also known as angiotrophic large cell lymphoma, is a rare disorder where neoplastic lymphoid cells proliferate within the walls of small- to medium-sized blood vessels. Peripheral neuropathy and other neurological manifestations, including stroke and dementia, are common, but cases of isolated multiple mononeuropathies in the absence of systemic symptoms are distinctly rare. We present an unusual case of biopsy-proved angiotrophic large cell lymphoma presenting exclusively with multiple mononeuropathies.

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